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Monoclonal antibodies are proteins that are engineered to detect and bind to other proteins that are present on cancer cells and that aim at thwarting a cancer's ability to grow.
For example, anticancer therapies could be engineered to detect and respond to complex cellular conditions in individual cells with high specificity.
Additionally, a two cell population, E. coli consortium-based biosensor was engineered to detect and integrate three environmental signals via intercellular communication.
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For example, a microbe could be genetically engineered to detect a particular pathogen and kill it, for example, the bacteria Vibrio cholerae that causes cholera.
Several biosensors have been developed and engineered to detect the presence of all types of AHLs.
Nonantibody scaffolds such as designed ankyrin repeat proteins (DARPins) can be rapidly engineered to detect diverse target proteins with high specificity and offer an attractive alternative to antibodies.
Starting from basic one-input responsive transcriptional or post-transcriptional gene control systems, the field has reached a level on which cells can be engineered to detect cancer cells, to obtain control over T-cell proliferation, and to restore blood glucose homeostasis upon blue light illumination.
Can bacteria be engineered to detect cancer in your body?
These DNA scanners can also be engineered to detect designer pathogens altered to be more deadly.
Cells engineered to detect a cancer-associated marker produce a protein that sensitizes them to an anticancer drug.
He adds that these paper-based diagnostics can be engineered to "detect antibiotic resistance or viral infections such as Ebola".
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