Exact(8)
While several scaffolds have been proposed for skeletal muscle regeneration, multiscale hierarchical scaffolds with the complexity of extracellular matrix (ECM) haven't been engineered successfully.
Bacillus subtilis has been engineered successfully to express heterologous antigens for use as a vaccine vehicle that can elicit mucosal and systemic immunity response.
This ScFv was engineered successfully with a biotin mimic tag (11 amino acid peptide) and cloned in the pET22b+ expression vector.
Traditionally, whilst targeted gene correction is able to restore point mutations entirely, it remains to be seen as to whether a strategy for the 'correction' of frame shift deletions may be engineered successfully.
This particularly holds for well-known microorganisms from the traditional sugar-based biotechnology, including Escherichia coli, Corynebacterium glutamicum and Saccharomyces cerevisiae which have been engineered successfully to produce a broad range of products from glucose.
These peptides were engineered successfully to abolish their agonist functions while retaining parasiticidal activity, opening new research possibilities.
Similar(52)
The engineered Salmonella successfully localized to tumor tissue and gene expression was dependent on the concentration of inducer, indicating the feasibility of peripheral control of bacterial gene expression.
Recently, we demonstrated that another engineered endonuclease successfully targets an endogenous locus in maize, generating heritable deletions at the endogenous target site [ 34].
Recently, silicon-based quantum dots have been engineered and successfully used in vivo as part of multimodal diagnostic and therapeutic agents targeted to tumors with antibodies and peptide ligands.
As expected, all these engineered strains successfully accumulated multiple α-alkenes, including 1-tridecene, trideca-1,6-diene, 1-pentadecene, pentadecene-1,8-diene and heptadeca-1,10-diene, which correspond to the decarboxylation products of the 14 0, 14 1, 16:0, 16:1 and 18 1 fatty acids, respectively.
An international team of scientists, led by Dr Lawrence Steinman of Stanford University, engineered and successfully tested a DNA vaccine in patients suffering from T1D. T1D features an intense autoimmune response that destroys the β-cells in the pancreatic islets of Langerhans, the site where insulin is produced and released.
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