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Specifically, we discuss how various CRISPR-Cas systems can be engineered and delivered using phages or phagemids as vectors.
To do this, we engineered and delivered MYOT-targeted artificial microRNA (miMYOT) vectors to knockdown mutant MYOT in muscles of an LGMD1A mouse model.
Hence, artificial miRNA sponges are often engineered and delivered by vectors as a way to investigate loss-of-function phenotypes or for therapeutic purposes (8, 17).
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STEP Offshore, a wholly-owned subsidiary of Aker Solutions, has won a contract from Awilco Drilling Ltd to engineer and deliver mud mixing and solids control systems to the Arctic II rig.
Veolia Water Technologies is to engineer, procure and deliver an industrial wastewater management system including its HPD Evaporators for Kinetic Hydrate Inhibitor (KHI) removal and distillate recovery at Dolphin Energy's natural gas production and processing facilities in Ras Laffan, Qatar.
To meet consumer demands, here's a few of the top developer tool startups trying to disrupt how companies engineer products and deliver them to you.
Their stilted, patrician delivery is from another age, yet some of these urban planners' and politicians' biggest preoccupations - notably with dirt, disorder and decency - and their near-utopian belief that a better, fairer city could be engineered on drawing boards and delivered from the top down finds an echo in much modern regeneration thinking.
Here we designed a dual-target therapeutic system in which MSCs were engineered to produce and deliver scFv-Fdt-tBid, a novel γ-SM-targeted immunoproapoptotic molecule.
Additionally, MVs may be engineered to express and deliver molecules that favor the reprogramming of resident cells toward regeneration.
The Ricketts family, who assumed ownership of the team in 2009, engineered a major culture change and delivered the goods in the seventh year of its regime.
This paper presents one of the few existing examples available to date of a reef restoration project designed and engineered to deliver risk reduction benefits.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com