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Experiments to genetically engineer expression of fish antifreeze proteins have not improved freezing tolerance of sensitive species.
The CMCF is responsible for processing patient leukemia cells and transfecting them with an adenovirus vector to genetically engineer expression of GM-CSF.
We designed multiple recombinant lentivirus vectors (LVs) and tested their ability to engineer expression of human α-galactosidase A (α-gal A) in transduced Fabry patient CD34+ hematopoietic cells.
In this study, we carried out preclinical validation studies using a novel lentivector to engineer expression of human IL-12 in acute myeloid leukemia blast cells isolated from 21 patients.
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ICa was virtually absent in CPC without engineered expression of Pim-1.
Recently, correlation between microvessel density and engineered expression of VEGF in human breast xenografts was observed.
Moreover, engineered expression of miR-224 and let-7i in K562 and K562R cells could significantly affect ST6Gal IV-induced proliferation rate and drug-resistance.
Although fungal laccases are well known and well characterized, only recently has in silico biology led to rapid advances in the discovery, characterization and engineered expression of prokaryotic laccases.
The aim of the present study was to determine whether unmodified hNPCctx could rescue visual functions and if engineered expression of a neurotrophic factor could enhance such effects.
It has been reported that the engineered expression of a heterologous marker (β-gal) protein leads to reduced fitness (Huang et al. 1991).
In order to enable delivery of macrolide-responsive transgene expression in a most compact format and a single transduction event we engineered expression of the macrolide-dependent transactivator ET1 and the desired target gene into a single AAV vector configuration.
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