Since axial loading of the tibia also engenders strains in the fibula, inclusion of the fibula in the analysis of these experiments would increase the usefulness of the non-invasive, dynamic axial loading model of the mouse tibia/fibula.
Our interpretation of these findings is that the frequent vigorous fighting that occurs between young adult males housed in groups could be sufficient to engender peak strains and strain rates that equal or exceed the stimulus derived from artificial loading.
Acquisition of resistance ability usually engenders a strain which, in the absence of a pharmaceutical intervention, is less fit than the sensitive strain [8], [9], [12], [35].
Three hours after each exercise period, right tibiae were subjected to 40 cycles of non-invasive axial loading engendering peak strain of 2250 με.
In the experiments reported here, a single 30-s period of dynamic loading engendering strains of physiological magnitude was sufficient to initiate a cascade of events culminating days later in measurable increase in bone formation.
"Even if you persevere with the eye strain engendered by reading scientific papers, the only thing you'll discover is that there is as much agreement about the causes of schizophrenia as there is agreement about the meaning of Shakespeare's plays".
These faults appear to have evolved since the Pliocene as part of a distributed dextral strike-slip shear zone in response to local strain engendered by the diverging movement of the Carboneras Fault to the north, and the Yusuf and Alboran Ridge faults to the south.
Bone architecture adapts to changes in the mechanical strain engendered within it and by this means ensures that it becomes, and is maintained, sufficiently strong to withstand the loads to which it is subjected [1].
The strain engendered at each load (N) was significantly less in the male and female Lrp5 HBM+ mice compared with their WT HBM− littermates (p < 0.01) and significantly greater in the male and female Lrp5 −/− mice compared with their WT+/+ littermates (p < 0.01).
The mechanostat is primarily a local phenomenon with local changes in loading-engendered strain culminating in local bone adaptation [2].
