Sentence examples for engaging cell death from inspiring English sources
E2F1 has a putative oncogenic signaling in DLBCL in the current series by orchestrating and engaging cell death pathways either alone or in cooperation with cellular proliferation pathways.
Furthermore, our multiparameter analyses of the kinetics of taxol responses in cells with differential capacity to rapidly engage cell death may indicate new rationales for combining taxol with other anticancer agents.
The results also suggest that the net effectiveness of low doses of taxol will be driven primarily by the proliferation kinetics of a tumour cell population despite any differential capacity to rapidly engage cell death pathways as a consequence of genetic status.
Cancer cells have also developed a variety of means to disable the trigger that engages cell death.
Therapeutics that engage programmed cell death in tumor cells have promise for the treatment of cancer.
High doses (10X IC50) of MeSter led to pycnotic parasites, suggesting that they had already engaged a cell death process.
As yet, perinatal PMF loss in mice most frequently engages apoptotic cell death, whereas within the postnatal ovary, oocytes in growing follicles undergo atresia, a less 'molecularly' defined death, carrying hallmarks of both apoptosis and autophagy.
For example, the TP53/p53-dependent TP53/p53-dependentonly deficient in 50% to 70% of papoptosisith ovarian cancer and the failure to engage apoptotic cell death wasld thus appear to be an important mecommonlyof the resistance to this type of cancer.
The idea that drugs with different modes of action initiate conserved responses which engage a programmed cell death is discussed.
Although they do not divide, senescent cells are viable, metabolically active and do not engage in programmed cell death (apoptosis) [ 7].
In addition, these cells had an abnormal morphology and fragmented nuclei and contained multiple large vacuoles, suggesting they were engaged in a cell death process and Additional file 3B).
