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Consider the alternatives (1) the lady already exhausted by carrying around her 328-page copy of Vogue, tries to do the housework and topples over into the bathtub; (2) she engages a second new maid, who fails to show up, or arrives at 9 A.M., eats breakfast and quits.
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If Ms. Queler thinks a singer might cancel, she will often engage a second, "secret" cover to go in for the Carnegie Hall performance.
While engaging a second, he took cover behind a generator which was struck by a rocket propelled grenade, and Romesha was wounded in the neck, shoulder and arms by shrapnel.
Due to the threat of invasion three reserve groups were mobilised, the first consisted of 2,737 police pensioners who were re-engaged, a second reserve of 5,380 Special Constables serving on a temporary full-time basis for the duration of the war, and 18,868 War Reserve Constables employed on the same basis as the Special Constables.
In both cases, this change can be attributed to the extra interaction provided by the tridentate ligand PMDETA, which provides the Na/K atom with a four coordinate (N×4) environment without the need to engage a second TMP bridge.
This is unlikely to come from another pair of lysine residues engaging a second CR domain since (i) it is only half of the expected energy of such an interaction, and (ii) there are no other pairs of lysine residues on the receptor-binding domain that have been shown to be critical for binding.
Although CRYs are known to not engage a second cofactor (Zoltowski et al., 2011; Xing et al., 2013), our previous cell-based random mutagenesis screen has identified three residues within this secondary pocket (Gly106 and Arg109 in CRY1, Glu121 in CRY2), whose missense mutations effectively abolished the repressor activity of CRYs (McCarthy et al., 2009).
The latter result contrasts with the fact that, in terms of neurite growth, p65/GITRL expressing neurons are significantly larger than those expressing p65 alone, suggesting that this is due to GITRL engaging a second signal that opposes NF-κB and leads to NGF-promoted neurite growth.
For on Sunday, the adman engages in a second career, conducting healing ceremonies for a rotating cast of clients.
One path could lead to Hartford, the other to Washington if she engages in a second battle against Mr. Shays.
Twenty-one percent of boards engaged a third party in 2016.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com