Sentence examples for engagement of endogenous from inspiring English sources

Collectively, these findings indicate that microparticle-A2MG activated endogenous host protective mechanisms that assure an efficient leukocytic response, mainly involving neutrophils and possibly macrophages, with effective clearance of the pathogen and the timely and efficient onset of resolution, with selective engagement of endogenous resolution pathways, leading to increased survival.

Cells responded to these different anti-inflammatory signals in a strikingly similar fashion, which suggests the engagement of a central endogenous system responsible for uncoupling selected neutrophil inflammatory functions.

Although the CDR2-containing epitope does not seem to be involved in the binding of endogenous cognate ligands (CD80 and CD86) and mAb engagement would not be antagonistic, the epitope might present an allosteric site for non-competitive inhibition.

Indeed, in Trex1−/− cells, type 1 IFN activation has been attributed to engagement of pattern-recognition receptors by cytosolic DNA, which may originate from DNA-repair processes or replication of endogenous retroviruses/retroelements.

Interestingly, the engagement of DR4, DR5, and DcR2 can activate the NF-κB pathway [ 20, 21], and high levels of endogenous NF-κB activity interfere with TRAIL-induced apoptosis.

Taking into account that it has been proposed that TCR engagement by endogenous Sags would be one epigenetic factor that contributes to the selection of murine pre-neoplastic T cell clones [31] we first investigated whether lymphomas bearing Vβ chains that recognize endogenous Sags were overrepresented in spontaneous AKR/J lymphomas.

Knockdown of endogenous G9a reduced cell proliferation.

Role of endogenous cannabinoids in synaptic signaling.

The word is an amalgam of endogenous, meaning made by the body, and morphine.

Maeder, M.L. et al. CRISPR RNA-guided activation of endogenous human genes.

d, RT qPCR analysis of endogenous BRD4 mRNAs.