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Although these indicators reflect sustainability concerns of these stakeholders, additional monitoring and stakeholder engagement are needed to support the continual improvement that is part of adaptive management.
To evaluate the biochemical effects of novel BACE1 inhibitor candidates, biomarkers that reflect target engagement are needed [ 6].
With growing calls for changes in the field of risk assessment, improved systematic approaches for addressing environmental issues with greater transparency and stakeholder engagement are needed to ensure sustainable trade-offs.
Predictive biomarkers along with pharmacodynamic markers of target engagement are needed to understand the mechanisms of action, discern optimal biologic dose, and identify the patients most likely to respond to a metronomic approach, and to anti-angiogenic therapies in general.
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More political engagement is needed.
A new policy of "conditional engagement" is needed.
The worse the Russian behavior, the greater the "proof" that more engagement is needed.
Mr. Forbes insisted in both cases that a tough engagement was needed, setting rules that the Clinton administration had never made clear, and that punitive action could wait.
Public calls for restraint and private telephone calls to Middle East leaders by President Bush and General Powell can help, but more active engagement is needed now.
But as is obvious from this debate, more engagement is needed still.So hold the games in Beijing in spite of, because of or irrespective of China's government.
There has been a vocal opposition to the push for constitutional recognition, including from some Indigenous people, but Peris said there was a lot of confusion around the official government-funded Recognise campaign, and greater engagement was needed with grassroots groups.
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