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Thus, when α-Syn binds to membranes and is engaged to form aggregation nuclei, the sequence needed for interaction with synphilin-1 is occupied and no longer available.
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More than one centrosome can bind to the same nucleus (Fig. 6), and combinations of daughter centrosomes engage nuclei to form mono- bi- and multi-polar spindles (Fig. 7).
If caspase activation is inhibited, RIP1 engages RIP3 to form the necrosome signaling complex and switches cell death from apoptosis to necroptosis.
ATG9 has been shown to self-oligomerize and was also detected in an asymmetric distribution on autophagic membranes., Therefore, we included a process wherein PtdIns3P- or PtdIns 3,5 P2-bound WIPtdIns 3,5 P2-boundto form a complex [ATG9-WIPI1/2-PtdIns3P or ATG9-WIPI1/2-PtdIns(3,5)P2] and thengages9 within this complex is ATG9vatod through multiple steps.
Digital diplomacy will no longer be about a certain élan on Twitter, it will be about identifying non-state actors and the channels of their choice, with which to monitor and engage with them to form new relationships.
However, owing to minor differences in the Cullin box motif, some proteins such as VHL engage Cul2 Rbx1 instead to form CRL2 complexes [ 48].
The microenvironment that metastatic cells engage and take advantage of to form a niche is a significant contributor to metastatic outgrowth.
When the New York Yankees visited the Oval Office this spring to be honored for winning the World Series, George W. Bush, true to form, engaged in some good-natured banter with the Yankees' principal owner, George Steinbrenner.
The debates — witty, raucous, bawdy — gave a community of politically engaged Russians a chance to form the kinds of rivalries and allegiances that the Putin administration was working to dissolve.
As the trial gets under way, Mr. Netanyahu is engaged in delicate negotiations to form a governing coalition after the January elections in which Mr. Lieberman ran as Mr. Netanyahu's No. 2 on a rightist ticket.
People remained "indifferent" to the government, so to engage them, he started to form district councils with representatives from every sizable village.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com