As a cell engages the surface it will bind to a finite number of integrins and apply an initial force at a few sites.
A crystal structure obtained for the binary complex of PPP1R15B and PP1 demonstrated that the N-terminal half of PPP1R15's functional core extensively engages the surface of PP1 following an itinerary previously observed for the regulatory subunit PPP1R9/spinophilin (Ragusa et al., 2010; Chen et al., 2015).
gB-NT is presumably displaced from gH/gL after virions engage the cell surface.
Pathogen adhesion occurs in two ways: (1) adhesins directly engage the host cell surface receptor, that is, Listeria spp. [ 37], Yersinia spp. [ 38, 39], and Neisseria gonorrhoeae [ 39, 40], and (2) bacterial connections form indirectly with the host receptor via the recruitment of extracellular matrix proteins (e.g., S. aureus) [ 16, 41].
Properly accomplished, the user will discern a light "drag" on the gage as the lightly-rounded gage ends engage the bore's surface at it's largest diameter.
Accordingly, small molecules that engage the composite actin-PP1 surface might serve as specific inhibitors of eIF2aP dephosphorylation to reverse the aforementioned failure of homeostasis, without affecting the many other PP1-containing holophosphatases in the cell.
Since β-CD has higher affinity on ZnO surface than dye molecules, β-CD molecules could be adsorbed on ZnO surface and engage the active sites.
It was inevitable that the translucent nature of the marble surface should engage the attention of Rodin, and even though he always prepared the models in clay and left the execution in stone to assistants, such marbles as "The Kiss" (1886), when properly exhibited with light partly from the rear, appear to glow with the incandescence of their passionate intensity.
Also labelled are the residues of this extended surface that engage the U U steps in RydC (N13, R16, R17, F39; F39 and N13 are not visible in this view).
The mid-nineties were years that seemed politically engaged on the surface.
