To summarize, we have found that bilateral lesions of DLPFC in rhesus monkeys do not impair performance on several tests of visual memory and decision-making that have been shown to require frontal temporal interaction, and engage some cognitive functions that have been associated with neural activity within the DLPFC.
We conclude that specific, enduring, structural brain changes in adult humans can be induced by biologically relevant behaviors engaging higher cognitive functions such as spatial memory, with significance for the "nature versus nurture" debate.
DeVito and colleagues (2012) used fMRI to examine changes in neural activity related to the Stroop color word interference task, which engages cognitive control and executive attention functions, in patients with substance use disorders that included AUD.
Simultaneity of listening and speaking engages complex cognitive functions.
The insular cortex is a limbic integration region engaged in emotional and cognitive functions.
To directly compare the brain regions engaged by these two cognitive functions, the same set of subjects consecutively participated in tasks of working memory and spatial attention while undergoing functional MRI (fMRI).
"We know that older women who are socially engaged have better cognitive function and a lower risk of developing dementia later, but too much of a good thing just might be bad," Dr. Margery Gass, executive director of the North American Menopause Society, said in a statement.
By showing how damage to a certain brain region affects system-wide connectivity, we can learn something about the intrinsic architecture of cortical circuits engaged in sensory, motor or cognitive functions (Nomura et al., 2010).
The ability to appreciate and engage with music remained intact even as cognitive functions deteriorated.
Let us first analyze spontaneous mental dynamics in a stationary environment where the brain is not engaged in a particular cognitive function, i.e., resting-state brain dynamics.
These findings, together with our observations that 5-HT6 rengagers engage mTOR in neurons of the PFC, a structure critical for numerous cognitive functions, encouraged us to explore the role of prefrontal mTOR in cognitive impairments induced by 5-HT6 agonists.
