The level of 'on state' of AcBax is also lifted higher in contrast to Direct Model I. Bax auto-activation can also enforce model's robustness of the bistability.
The control was trained identically to D iscern, but did not include features for structural neighbors or the INTREPID phylogenomic conservation scores, nor was any attempt made to enforce model sparsity.
It was previously shown that sparse models of regulatory networks can accurately capture the topology and dynamics, and that using L1 shrinkage (and variations such as the Elastic-Net) can be used to enforce model parsimony (Greenfield et al., 2010; Gustafsson and Hörnquist, 2010).
Sara Ziff, an American model and filmmaker, recently initiated the Model Alliance to protect and enforce models by devising a Models' Bill of Rights.
The current self-enforcing model implies close correlation of histone modifications and DNA methylation, especially the crosstalk between methyl-H3K9 and DNA methylation [ 3].
These essential components of the biomass were kept in the ColiPrunedComp model, however, network compression enforced the model to compress the two steps of uptake and consumption of a trace element into one step by integrating the required amount of external trace elements directly in the BSR of ColiPrunedComp.
Notably, unofficial outlets are the only source of life-saving medications for many rural residents in locations where enforcing laws modeled on wealthy societies could do more harm than good.
In the developed model, the constraints on different parameters that enforce appropriate model dynamics vary widely from some very tightly controlled parameters to others that are almost arbitrary.
We implemented F l u χ using an existing WMS, that was adapted to enforce our model and triggering semantics, and adopted, as the underlying data store, the HBase tabular storage [8].
