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The company's Zephyr air quality sensors took pollution measurements before, during and after an experiment, to gauge the impact of enforcing car-free zones, using hedges to block pollution and making use of different kinds of transport.
In mice, xenotransplants of colon cancer cells with enforced CAR expression formed significantly smaller tumours, whereas CAR inhibition increased the formation of liver metastases.
Enforced CAR expression led to lower caspase 3/7 activity in DLD1 cells upon treatment with TRAIL, whereas no changes were found in HCT116 and SW620, and an increase in the SW480 cell line was found (data not shown).
In cancer cell lines, CAR inhibition resulted in increased proliferation, whereas enforced ectopic CAR expression led to opposite results.
These experiments showed that RNAi-mediated CAR knock down resulted in increased proliferation, migration, and invasion of gastric cancer cell lines, whereas enforced ectopic CAR expression led to opposite effects.
This year, the government responded by drawing new parameters to enforce basic car safety norms through mandatory side-impact and frontal crash tests.
Similarly, motoring organisations passionately oppose limiting the amount of fuel used by drivers, for instance by banning or specially taxing certain kinds of car, or enforcing the 70mph speed limits.
Imagine dying in a starfish shape on the bonnet of a slowly moving car, while enforcing a parking rule that absolutely doesn't matter.
Government troops, tanks and armoured cars are enforcing a forbidding cordon around the desert circuit.
Of course, ornery commuters have been enforcing de facto quiet cars since the dawn of the mobile age.
In Rome, officials are enforcing a policy whereby cars with odd or even numbers on licence plates are banned on alternate days during the three day period.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com