Sentence examples for enforced the expression from inspiring English sources

When we enforced the expression of miR-532-3p miR-532-3p miR-532-3pe minocardiomyocytesion and deathecells were significantly increased in response to the low-dose DOX (0.2  μmitochondrial

A major approach to HIV eradication envisions antiretroviral suppression, paired with targeted therapies to enforce the expression of viral antigen from quiescent HIV-1 genomes, and immunotherapies to clear latent infection.

Blocking Stat3 in highly metastatic melanoma cells suppresses the invasion of the cells and lung metastases; enforcing the expression of cStat3 converts poorly metastatic melanoma cells into highly metastatic cells [7].

For this reason, it is eligible to inhibit the NF-κB activation and enforce the expression of the proapoptotic genes ensuring the elimination of tumor cells.

We then investigated the therapeutic potential of TEMs in the HLI model by enforcing the expression of TIE2 on BM-derived macrophages (BMDMs) using a Pgk- Tie2 LV (Fig 5A).

The interplay between the REST complex and miR-124 sets up a feedback loop which stabilizes and enforces the expression of neuronal vs. non-neuronal genes (Fig. 2B) [ 74, 76].

Ex vivo expansion of leukemia-specific T cells that are genetically modified to enforce the expression of a pre-selected TCR can also provide large numbers of T cells with exquisite specificity.

Transfer of autologous T cells transduced with retrovirus to enforce the expression of a CD19-specific CAR containing the CD28 and CD3-ζ endodomains after a preparative chemotherapy regimen led to the prolonged eradication of CD19+ cells in a follicular lymphoma patient [92].

One problem with Article 80 is that it relies on Member State law to define and enforce the free expression rights guaranteed by the European Charter.

Interestingly, noise also enforces the coordinated expression of genes across large regulons, 28 all this implying that any noise change may have profound consequences.

Using computational approaches to explore our gene-expression data sets, we found that NRAS(G12V) enforced the leukemia self-renewal gene-expression signature and was required to maintain an MLL-AF9 and Myb-dependent leukemia self-renewal gene-expression program.