Sentence examples for enforced induction of from inspiring English sources

Further, enforced induction of autophagy transiently induced C/EBPβ and cytokine mRNAs.

Correspondingly, TRAIL-based therapies to eliminate human cancer cells via enforced induction of apoptosis have been established and represent a promising approach in anti-cancer research.

The Experimental Induction of Out-of-Body Experiences.

In conclusion, we have shown that by genetic engineering, controlled dimerization and tumor targeting can be combined to create bifunctional fusion proteins with enforced apoptosis induction under maintenance of systemic tolerance, which exceeds the functional activities of conventional and other antigen-targeted TRAIL molecules.

Inhibition of SBHA-mediated induction of BimS by enforced expression of B-RAFV600E was also mirrored at the protein level.

Our results show that both targeting and controlled dimerization of scTRAIL fusion proteins provides a strategy to enforce apoptosis induction, together with retained tumor selectivity and good in vivo tolerance.

Another study shows that enforced HBx suppresses RASSF1A possibly via induction of DNMT1 and DNMT3B expression [ 106].

Moreover, we estimated the effect of enforced expression of DN-CHOP on active caspase 3 induction in Scd1-silenced U2OS.

We find that induction of both KROX20 and OCT6 is impaired, whereas enforced expression of KROX20 drives both myelin gene expression and cell cycle arrest in Merlin-null cells.

Genes that play important roles in the G1/S transition and initiation of DNA replication, including CCNE, CDK2, CDC6, CDC45, CDC7, RFC subunits, and MCM family members, were down-regulated at 6 and 24 hr post-IR as an expected consequence of the p53-dependent induction of CDKN1A (p21Waf1) to enforce the G1 checkpoint response.

Oncolytic viruses enforced with apoptosis induction or with the inhibition of oncogene products are currently tested.