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There were strict, legally enforced guidelines regarding the degree of freedom permitted to the cast and crew.
Fashion conglomerates LVMH and Kering issued a charter in September 2017 that enforced guidelines surrounding size and age.
The study hypothesis is that procalcitonin-guidance is non-inferior (i.e., at worst a 7.5% higher combined failure rate) to the management with enforced guidelines, but is associated with a reduced total antibiotic use and length of hospital stay.
Given the size of the data sets being deposited in the SRA, it is unfortunate that more strictly enforced guidelines on these metadata have not been provided, along with the use of agreed vocabularies and ontologies.
This ongoing multicenter trial is the first prospective, randomized controlled trial in hospitalized patients with LRTI sufficiently powered to show non-inferiority of a PCT guided antibiotic management compared to enforced guidelines.
The goal of this ongoing trial is to show non-inferiority of the PCT guided antibiotic management approach in comparison to enforced guidelines for the primary endpoint (i.e. the disease-specific failure rate within 30 days).
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Patients were randomly assigned to an intervention group, where guidance of antibiotic therapy was based on PCT cut off ranges or to a standard group where guidance of antibiotic therapy was based on enforced guideline recommendations without knowledge of PCT.
Patients were randomly assigned to an intervention group, where guidance of antibiotic therapy was based on procalcitonin cut-off ranges, and to a standard group in which guidance of antibiotic therapy was based on enforced guideline recommendations without knowledge of procalcitonin.
The state legislature has shied away from enforcing guidelines for urban development in the Phoenix area.
Many societies seem hesitant to enforce guidelines across their respective communities because they believe ethical issues are best dealt with on a case-by-case basis.
Much like Apple took over the computing industry by incorporating hardware and software with design and user experience in mind, successful blockchains will need to do better in enforcing guidelines for developers.
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