Sentence examples for enforce the expression from inspiring English sources
For this reason, it is eligible to inhibit the NF-κB activation and enforce the expression of the proapoptotic genes ensuring the elimination of tumor cells.
Ex vivo expansion of leukemia-specific T cells that are genetically modified to enforce the expression of a pre-selected TCR can also provide large numbers of T cells with exquisite specificity.
Transfer of autologous T cells transduced with retrovirus to enforce the expression of a CD19-specific CAR containing the CD28 and CD3-ζ endodomains after a preparative chemotherapy regimen led to the prolonged eradication of CD19+ cells in a follicular lymphoma patient [92].
Blocking Stat3 in highly metastatic melanoma cells suppresses the invasion of the cells and lung metastases; enforcing the expression of cStat3 converts poorly metastatic melanoma cells into highly metastatic cells [7].
When we enforced the expression of miR-532-3p miR-532-3p miR-532-3pe minocardiomyocytesion and deathecells were significantly increased in response to the low-dose DOX (0.2 μmitochondrial
We then investigated the therapeutic potential of TEMs in the HLI model by enforcing the expression of TIE2 on BM-derived macrophages (BMDMs) using a Pgk- Tie2 LV (Fig 5A).
The interplay between the REST complex and miR-124 sets up a feedback loop which stabilizes and enforces the expression of neuronal vs. non-neuronal genes (Fig. 2B) [ 74, 76].
To identify genes whose products enforce heterochromatin, the expression of a reporter localized at pericentromeric heterochromatin was measured in mutagenized backgrounds in Drosophila (suppressor of variegation screens).
Interestingly, noise also enforces the coordinated expression of genes across large regulons, 28 all this implying that any noise change may have profound consequences.
Our results suggest that micronutrient deficiencies might also function as a "hit" which in conjunction with oncogene expression can enforce the cancerous process.
Our results suggest that folate deficiency functions as a non-genetic hit which in conjunction with oncogene expression can enforce the cancerous process.
