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Drug developers tightly enforce parameters on who can participate in these trials, citing concerns about safety and the validity of the research.
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The impact of the pact is nullified by this reluctance to enforce strong parameters.
Traffic shapers such as Dummynet [7], NetEm [8], ModelNet [9], or NISTNet [10] can enforce such parameters on real IP packets that pass through the shaper.
baseml file to enforce the same parameters across partitions.
In the developed model, the constraints on different parameters that enforce appropriate model dynamics vary widely from some very tightly controlled parameters to others that are almost arbitrary.
Instead of scaling the cognitive impairment scores post-estimation, we performed an equivalent linearly scaling of the ADAS-Cog item parameters to enforce these measurement scales for estimation of memory, language, and praxis impairment.
with λ a regularization parameter to enforce smoothness of g z) (see [28, 31]), and with є a small positive number.
An explicit corrective velocity scheme for PMC enforcement is introduced, and its parameters optimized to enforce a specified PMC criterion with minimal corrective velocity magnitudes.
To prevent unlimited drifting, limits on the maximum displacement from the original tree position were enforced (Section 'Simulation parameters').
Parametric distortions are employed with parameters calibrated to enforce the absence of acceptable opportunities in the options market for the S&P 500 index.
Perfect adhesion along the undelaminated portion of the delamination plane is simulated by treating interface stiffnesses as penalty parameters, whereas to enforce interface displacement continuity between plate elements constituting each sub-laminate above or below the delamination plane, the Lagrange multiplier method is used.
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