Sentence examples for energetic landscape from inspiring English sources

Drugs inhibit proton conduction by binding to an aqueous cavity adjacent to M2's proton-selective filter, thereby blocking access of proton to the filter, and altering the energetic landscape of the channel and the energetics of proton-binding to His37.

This protection of quantum coherence can arise from multiple mechanisms, but the net effect is the same: the energetic landscape is course-grained thereby improving efficiency by effectively smoothing the rugged energetic landscape while simultaneously eliminating trap states.

Within the energetic landscape of a spinel ceramics-conductor system (see Fig. 4), such degradation process is revealed as subsequent transitions between a set of wells (basins) tending towards overall thermodynamic minimum within the same metabasin.

Here, we investigated the structural basis and energetic landscape of the susceptibility difference between the three HLA II isotypes to AR by combining computational analysis and experimental assay.

The conformational space and energetic landscape for this reaction are analyzed without a priori assumptions about the protonation states of the different residues during the reaction.

In an energetic landscape view, particles must undergo an energy barrier-crossing event in order to successfully convert from Prohead-II to EI-I.

Compared to interaction in solution, anchoring of proteins into the membrane severely changes the energetic landscapes of protein protein interaction.

Mechanistic coupling of reactions as suggested here can flatten energetic landscapes and diminish thermodynamic barriers and can be another role for enzymatic complexes common in nature and a useful tool for metabolic engineering.

We speculate that this cooperativity, and thus, indirectly, the topology rate relationship, may have arisen in order to generate the smooth energetic landscapes upon which rapid folding can occur.

Upon grafting the energetic landscapes inside the pores change significantly while the calculated isotherms reveal that in general the density of the adsorbed phase increases with increasing surface oxygen content.

Hence, along with above-mentioned epigenetic modifications, crowding conditions should also be accounted for when studying conformational dynamics and energetic landscapes of folding/unfolding and gene regulatory mechanisms involving iMs.