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A coupling parameter, calculated from IC50 values, will be 1 if the residue has no structural or energetic effect on the ligand binding group.
Here, in Saccharomyces yeasts, we report a very strong inverse association (r = −0.951, P < 0.004) between the genome-wide frequency of substitutions and their average energetic effect on nucleosome formation, as predicted by a structurally based energy model of DNA deformation around the nucleosome core.
Fish liver oil: Studies suggest that this Nutraceutical may have an energetic effect on the ovaries and restore normal ovulation and menstrual cycle.
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However, this does not respect the energetic effect of sound on the auditory organ, as well as the neuropsychic and cardiovascular system of humans and sensory-motor functions.
Since we did not know the energetic effect of different spacings on the complex initially, we treated all spacings equally.
The black hole's existence can be inferred from its energetic effects on an envelope of gas swirling around it at extremely high velocities.
In particular this method has been also recently improved [17] by a more complete estimation of the plants and their energetic effects on the system.
Because these objects cannot be observed directly--and small ones are particularly difficult to detect--astronomers must measure their gravitational or energetic effects on nearby stars or surrounding material.
We found no significant correlations between ΔDE and mutational frequency, supporting the idea that mutations in these lines may be accumulating without any regard to their energetic effects on nucleosome formation.
The detrimental energetic effect of retro-inverso isomerization of an α-helical l-peptide on its target protein binding has been estimated to be 3.0 3.4 kcal/mol.
Taken together, we conclude that the effect of ionic strength and applied transmembrane potential on the energetics of gating fluctuations is small, as compared to the energetic effect of temperature.
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