Main Outcome Measures: Gait function (speed, endurance, walking status, use of assistive device and orthotics); oxygen costs of walking; brain motor control assessment; self-report indices; ASIA classification; muscle function test; and safety.
We initially hypothesised that these SNPs would be associated with endurance athletic status.
We have also shown that several SNPs within EPAS1 are associated with endurance athletic status, in a sex-specific manner.
However, only rs11689011 was associated with endurance athletic status in the Polish sample, while this was not the case for rs1867785.
We did not have any directional hypothesis for rs11689011 either, due to the conflicting results reported for this SNP (the T allele in rs11689011 was associated with endurance athletic status in elite Australians on one hand, and with lower hemoglobin concentrations in Tibetans, on the other hand) [ 9, 12].
In normal-weight subjects, several studies have indicated that the resynthesis of substrates such as PCr depends on several factors (endurance fitness, training status) [26, 30], factors that may affect the energy profile of muscle during subsequent exercise.
Specifically, the majority of studies suggest that exercise can produce mild-to-moderate benefits on aerobic endurance, strength, functional status, and quality of life [ 7, 23, 24].
We found a significant association between IGF2BP2 rs4402960 and LPL rs320 and athletic status; endurance athletes are less likely to have the metabolic risk IGF2BP2 T and LPL rs320 G alleles compared with sprint/power athletes and controls, respectively.
Sung [ 58] investigated changes in multifidi muscle endurance and functional status after a 4-week supervised spinal stabilization exercise program in 16 patients presenting with chronic low back dysfunction (LBD).
They were allocated to two groups according to their training status (endurance-trained cyclists: N = 20; non-trained individuals: N = 20).
