Sentence examples for ends of target from inspiring English sources

Here, we tested whether there was statistical difference in the localization of engaged nucleotides in the sequence of steps of transcriptional analysis between 3' and 5' ends of target sites of AONs of the same grade.

As the L4_AND score did not show the best ability to correlate AON efficacy and efficiency in both sets, AON efficacy and efficiency is more attenuated by presence of engaged nucleotides at the ends of target sites than at other sites.

DOI: http://dx.doi.org/10.7554/eLife.03700.012 Sequences at the ends of target exons specify where ligamers bind.

Such processes are generally mediated by microhomologies (< 25 bp homology) at the ends of target sequences similar to the termini microsatellites of mSDs found in this study.

Motivation: The Illumina paired-end sequencing technology can generate reads from both ends of target DNA fragments, which can subsequently be merged to increase the overall read length.

Second, we compute two heuristic metrics that seek to tie in the end goal of target detection/tracking with the rate adjustment scheme.

Updated at 10.02am GMT 9.55am GMT Spain bond sales hit top end of target Sticking with Spain for the moment, the Government sold €4bn of three and nine month bonds - the top end of its sales target.

miRNAs are small, non-coding sequences of 17 25 bp that regulate gene expression by binding to the 3' end of target mRNAs, resulting in the inhibition of translation of the mRNAs [2], [3].

The majority of described sRNAs regulate through a mechanism involving complementary base-pairing with the 5' end of target mRNAs, blocking access to the ribosome binding site and/or start codon.

To investigate whether engaged nucleotides at either 3' or 5' end of target sites affected AON efficacy and efficiency differently, we stratified the groups into 3' and 5', and repeated the same K-S tests, as discussed below.

In bacteria, base pairing of ncRNAs to the 5′ end of target transcripts is common.