Sentence examples for ends of spindle from inspiring English sources

Nonetheless, a sizable number of Qdot-labeled filaments, that were undeniably within the spindle proper (e.g., as in Fig. 6A B), also moved toward the plus ends of spindle microtubules.

This may be a consequence of the hydrodynamic drag of segregating chromosomes, and is consistent with EM tomography showing congregation of the plus ends of spindle microtubules during anaphase (O'Toole et al., 1999).

Mitotic chromosome segregation in eukaryotes involves the capture and stable attachment of the plus ends of spindle microtubules by all chromosomes in a manner that connects sister chromatids to opposing spindle poles.

The plus ends of spindle microtubules emanate into the cytoplasm to facilitate microtubule-mediated chromosome capture, whereas the minus ends are focussed at the two spindle poles formed by centrosomes.

Filopodia extended from the polar ends of spindle-shaped Ehrlichia-infected host cells (E.

Furthermore, when the bipolar meiotic spindles were assembled during the MI and MII stages, the p-MK2 signals were detected at the spindle minus ends, but not spread over the entire bipolar spindles, just near the minus ends of spindles (cytoplasmic p-MK2) (Fig. 2Ba,Ca); therefore, we refer to the cytoplasmic p-MK2 signals as being localized to the spindle minus ends.

Kinetochores are large multiprotein complexes that mediate chromosome segregation in all eukaryotes by dynamically connecting specialized chromosome regions, termed centromeres, to the plus-ends of spindle microtubules1,2.

Kinetochores bind the plus-end of spindle microtubules thereby establishing connections between sister chromatids and spindle poles.

Further analysis uncovered that these proteins safeguard the anchorage of the minus end of spindle microtubules to the centrosome/SPB [6], [7], [8].

This complex is conserved in fungi, in which it localises to the mitotic SPB and ensures proper spindle assembly; in particular it is required for the anchoring of the minus end of spindle microtubules to the SPB [11], [20].

We previously showed that in fission yeast, a mitotic-specific SPB component, Msd1 (mitotic spindle disanchored 1), is required for anchoring the minus end of spindle microtubules to the SPB 11.