Your English writing platform
Discover LudwigSuggestions(1)
Exact(9)
We have identified a nuclear factor that binds to double-stranded DNA ends, independently of the structure of the ends.
Upon DNA-PK activation, XRCC4, XLF, and DNA ligase IV (LIG4) are recruited to align and ligate the ends independently of sequence homology4.
However, it is possible that Ku, which has a strong affinity for duplex DNA ends in vitro42, binds DNA ends independently of chromatin or associated factors in vivo.
If separated, the two groups could pursue their ends independently, though a great deal of collaboration would still be necessary.
As shown in Figure 7F, Exo1 association at the HO-induced telomere was reduced in rif2Δ mre11Δ compared to rif2Δ mre11-nd cells, supporting the hypothesis that the MRX complex promotes Exo1 association at DNA ends independently of it nuclease activity.
The early steps of meiosis thus provide a simple and universal mechanism for identifying chromosome ends independently of the number, morphology, and sequence composition of the chromosomes in a given species.
Similar(51)
The present study investigated the placement of stickers on cars (front vs. side vs. rear end) independently of stickers' content.
Give the gift of indecision with a certificate good for a stay at any of the 440 high-end, independently owned hotels affiliated with Small Luxury Hotels of the World.
Can ch-TOG track MT plus-ends independently of TACC3?
Before nuclear envelope breakdown (NEB), MCAK localized to all MT plus-ends, independently of their position within the cell (Supplemental Fig. S 2b; Fig. 2b, c), but as soon as NEB was observed (as determined by chromosomes that had moved out of the nucleus), MCAK association with MT tips in the vicinity of chromosomes was strongly reduced (Supplemental Fig. S 2c; Fig. 2b, c).
The onsets and ends were independently determined by two experienced investigators and their results were compared.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com