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The application of sticky ends has been shown in fabrication of 2D and 3D structured arrays, as well as in complex 3D RNA nanostructures.
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Although the biological implications of these extensive modifications remain to be elucidated, adenylation at the 3'-end has been shown to enhance the stability of mature miRNAs [38].
C-terminal end has been shown to be important site of nucleophosmin/B23.
Although higher segmental mobility at the chain end had been shown above the Tg in our earlier work, this study found that the Tg,FTIRs of the M-PS and E-PS are the same.
Only three copies of these hexamers in the 5' end have been shown to be required for transposition [ 23].
The IAP at end-inspiration has been shown to be approximately four times greater in the surgical ARDS groups as compared with the medical ARDS group [34].
To that end, it has been shown that induction of autophagy results in selective degradation of catalase, leading to accumulation of mitochondrial ROS and ultimately cell death[27].
To this end, tacrolimus has been shown to have an impact on cancer signalling pathways such as the MAPK and the p53 pathway.
To this end, it has been shown that the NAD+/NADH ratio value fluctuates in response to changes in metabolism [ 44– 44].
Concomitant with aging in human cartilage, the accumulation of advanced glycation end products has been shown to decrease the susceptibility of this tissue to proteolytic degradation [ 30, 31].
Although there is a preferred position for the seed (in the case of miRNA, it is the 5′-end), it has been shown that seeds could also be on other positions (Brennecke et al., 2005).
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