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They allow replication of chromosome ends, an issue mostly about telomerase, which we seem to understand (though details of its regulation are works in progress).
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Floyd will play, and his inclusion may end an issue that has dogged Valentine since Thursday, when Floyd and his agent, Seth Levinson, claimed Valentine had promised Floyd he would take him in a telephone conversation last Tuesday.
Scheider, who only reprised his role to end a contractual issue with Universal, was also unhappy during production and had several heated exchanges with Szwarc.
For example, ending poverty — an issue GiveWell plans to tackle — requires long-term community development at the grass-roots level.
The ending raises an issue, not about separation of church and statement but about what may be construed as incompatible with what has preceded it.
Meals often ended with an issue de table, which later changed into the modern dessert, and typically consisted of dragées (in the Middle Ages, meaning spiced lumps of hardened sugar or honey), aged cheese and spiced wine, such as hypocras.
One debate, for example, will focus on whether tax cuts for the wealthiest families should expire as scheduled at year-end — an issue that could gain traction now that Mitt Romney, the possible Republican nominee, has disclosed that he and his wife paid an effective federal rate of just 13.9 percent on their huge 2010 income.
We must honor those who did and continue to do this work because they know it is, in the end, an issue of moral responsibility and not one of financial viability.
She said Dr. Cousin had a knack for bringing people on opposite ends of an issue together.
This protracted litigation, conducted at enormous cost, now comes to an abrupt end on an issue directly presented to this Court nearly eight years ago but not decided.
But he went out of his way to assert his leadership credentials towards the end, making an issue of the contest of character with David Cameron.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com