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The secondary endpoints (variation from baseline of serum creatinine concentration and eGFR level, or decrease in eGFR level from baseline ≥25%%) were investigated by regression models with adjustment for centres.
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(i) If the parasite clearance rate is used as an endpoint: Large variations in antimalarial blood concentrations may confound estimates.
In patients with septic shock, intravenous volume expansion was provided to achieve predefined endpoints: pulse pressure variation <13%[16]6], no response to passive leg raising [17] or no respiratory variations of the inferior vena cava diameter [18].
Sub-cluster 9 contained turn bias and normal body duration, both of which (unlike all previous endpoints) showed little variation between treatment groups (Fig. 7).
Main secondary endpoints were the variation in serum creatinine and eGFR values between baseline and 72 ± 24 h after MRI and the percentage of patients with a decrease in eGFR of at least 25%% from baseline.
The primary endpoint was BNP variation after fluid challenge.
According to this analysis, the endpoint HA score variation was greater with the CC genotype than with the AG/AA genotypes when the remission and non-remission groups were compared.
Main endpoint: Gender spatial variation was measured, as follows: SAVA estimated gender-specific utilization ratio; BYM estimated the fraction of variance attributable to spatial correlation in each gender; and, SCM estimated the fraction of variance shared by the two genders, and those specific for each one.
Difficulties in analysing disease progression include variation in endpoints (e.g., progression-free survival, locoregional control, tumour response, etc).
6 Strong conclusions were unable to be drawn due to the limited number of randomized studies and the larger variation in endpoints to define full or poor recovery.
Secondary endpoints were coefficient of variation (CV) of glucose (GluSD/Glucose mean, variability or mean of glucose during the first 24 hours, maximum glucose during ICU stay.
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CEO of Professional Science Editing for Scientists @ prosciediting.com