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Studying samples obtained during treatment with anti-invasive agents (or, indeed, any new agents) will allow researchers to evaluate the ability of biomarkers and cellular endpoints stemming from experimental studies to provide surrogates for drug response, an important aim in the absence of long-term outcome data.
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The comparatively long runtime of the endpoint detection stems from the exhaustive sliding window evaluation of each wall.
In practice, however, the available single substance data might have been recorded under slightly different conditions, using different endpoints or even stem from different species.
The latter consideration stems from toxic endpoints being dose-dependent [14,15], and animal models tend to use doses higher than the equivalent human doses.
We speculated that the contradictory regulation of MMP1 in Meta might stem from differences in prognostic endpoints investigated rather than the lesion sites.
The concern stems from certain epidemiology studies reporting an association, although particulars of endpoints and dosimetry are inconsistent across studies and several other studies show no such effects.
Inescapably, though, there is this idea underpinning the toy industry, as well as strains of modern pedagogy, that male and female children are fundamentally different, that their interests stem from and reveal a difference in their brains and that to object to this is the endpoint of politically correct foolishness, arguing about evidence that's in front of your own eyes.
Such caution stems from history.
This stems from two trends.
It stems from self-doubt.
Many of them stemmed from unpaid creditors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com