Sentence examples for endpoints reduction from inspiring English sources

Individuals were assessed at baseline and again at 6 months for primary endpoints: reduction of pain and an improvement in physical functioning.

Fremanezumab was significantly superior to placebo for the prespecified secondary endpoints: reduction in the number of monthly days of acute headache medication use for both monthly (-4.2 days) and quarterly (-3.7 days) versus placebo (-1.9 days); p<0.0001).

Two of the studies used the QALY as an outcome measure [ 17, 18], while the other studies presented the outcome in surrogate endpoints: reduction in alcohol consumption [ 14, 15] or number of successfully treated persons [ 16].

MOEs (margin of exposure) for the endpoints reduction in body weight gain, multinucleated giant hepatocytes in the liver, and reproductive toxicity were sufficiently large, even in the highest exposure group.

The serum levels of 8-OHdG were significantly reduced in high hydrogen groups (hydrogen concentration larger than or equal to 0.22 ppm) compared with the tap water control group F. However, opposed to the other testing endpoints, reduction levels and hydrogen doses were not correlated in pH 8.5 groups, suggesting that a dose response effect was not present for serum 8-OHdG (Table  2).

Across endpoints, reductions were greater with erenumab 140 mg than 70 mg.

Overall, 72% of patients had a baseline to endpoint reduction in HbA1c (range −0.1 to −2.8%), and 87% of antibody negative versus 62% of antibody positive patients had an HbA1c endpoint reduction.

If the endpoint reduction of gasoline is very severe, it did not generate a more significant reduction of sulfur in gasoline an LCO, even when additives were present.

Accordingly, our aim was to study the relationship between prior treatment and both baseline and 1-year echocardiographic LV mass in subjects enrolled in the Losartan Intervention For Endpoint reduction (LIFE) study.

Recent clinical trials such as Heart Outcomes Prevention Evaluation (HOPE), Losartan Intervention for Endpoint reduction (LIFE), and Study of Cognition and Prognosis in the Elderly (SCOPE) have indicated that blocking the renin-angiotensin system (RAS) may reduce the risk of developing type 2 diabetes mellitus.

A more definitive conclusion can though be drawn from the results of the Losartan Intervention for Endpoint Reduction (LIFE) study.