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We studied the case of Lm infection, focusing on transcriptional synergism by NF-κB and ISGF3, transcription factors at the endpoints of two major antimicrobial pathways.
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Osteogenesis was assessed by micro-CT and histology at two endpoints of ten and 30 days.
Mice were sacrificed at a defined endpoint of two weeks post diagnosis.
In total, 33 (94 %) of the 35 patients achieved the primary endpoint of two consecutive visits with a platelet count ≥70 × 10/L.
Historically, the criterion for achieving this approval is to meet the primary endpoint of two independent double-blind, placebo-controlled phase III trials.
HRQoL, assessed using the HAEMO-QOL set of questionnaires, was a secondary endpoint of two phase 3 multinational clinical trials, guardian™ 1 and 3 15, 15.
Lung injury score, wet/dry ratio, arterial oxygen tension, oxidative injury, and expression of pro-inflammatory mediators and apoptotic genes were assessed at the endpoint of two hours using the high-tidal volume protocol.
When the analysis was conducted for the more rigorous endpoint of two grades or more improvement (ie, improving to 0 ["no wrinkle"] or 1 ["shallow, just perceptible wrinkle"] on the NLF severity scale at day 3), the physicians and subjects also rated the treatments similarly at this clinic visit.
In supernatural graphs containing such paths, there is always another path and adding two gray edges between the endpoints of the two paths can create a cycle.
Whenever two unknown quantities are found in final equality, there results a locus fixed in place, and the endpoint of one of these unknown quantities describes a straight line or a curve.
By means of this construction Fermat was able to formulate the fundamental principle of analytic geometry: Whenever two unknown quantities are found in final equality, there results a locus fixed in place, and the endpoint of one of these unknown quantities describes a straight line or a curve.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com