Sentence examples for endpoints of tissue from inspiring English sources

Further resuscitation is exclusively guided by endpoints of tissue perfusion irrespectively of the presence of arterial hypotension ('permissive hypotension').

Dosimetric endpoints of normal tissues around target regions in both plans were not significantly different (P > 0.05) except for the optic chiasm (Table 2, Figure 4).

Dosimetry endpoints of normal tissues around target regions in both plans were not significantly different (P > 0.05) except for the optic chiasm.

Viral titers were determined using the median endpoint of the tissue culture's infectious dose (TCID50).

Ignoring one study where the subjects were selected as having a lesion [ 22], lesion prevalence in current snuff users was typically in the range 30 70%, though lower in two studies [ 45, 47] where the definition implied a more severe lesion, and in one study [ 31] where the endpoint of "soft tissue lesion" was not further defined.

The main endpoint was difference in degree of tissue filling between the defects in the patella and the condyles at each follow-up.

The aims of this viewpoint article are to critically evaluate limitations of current resuscitation endpoints and alternatively propose a three-step approach based on markers of tissue perfusion as resuscitation endpoints in shock of all origins.

During attempts to optimize single-organ/renal perfusion, maintenance of tissue perfusion-based endpoints needs to be guaranteed and the risk/benefit ratio of further increases of vasopressor doses must be critically weighed.

Current guidelines for hemodynamic management of severe sepsis and septic shock recommend the use of global markers of tissue hypoxia as resuscitation endpoints [ 1, 2].

In support of a poor correlation between macrocirculatory endpoints and tissue perfusion in shock, the majority of critically ill patients with sepsis continued to exhibit signs of tissue hypoperfusion despite reaching macrocirculatory endpoints (for example, mean arterial blood pressure of at least 65 mm Hg and central venous pressure of at least 8 mm Hg).

Accepting that all of these targets carry limitations and further parameters [ 36- 39] may be useful and even become the future tissue perfusion-based endpoints of choice, we suggest using a combination of the above-mentioned parameters as tissue perfusion-based resuscitation endpoints in shock of all origins (Table 1 and Figure 4).