Sentence examples for endpoints of choice from inspiring English sources

Accepting that all of these targets carry limitations and further parameters [ 36- 39] may be useful and even become the future tissue perfusion-based endpoints of choice, we suggest using a combination of the above-mentioned parameters as tissue perfusion-based resuscitation endpoints in shock of all origins (Table 1 and Figure 4).

Our endpoint of choice was the phosphorylation of myosin regulatory light chain (MLC20) in cultured human uterine myocytes.

Many studies have used PFS, DFS, or TTR as the clinical endpoint of choice.

The primary endpoint of choice in such trials should be cure and eradication at a predefined test-of-cure visit that postdates the end of treatment.

Overall survival (OS) is generally regarded as the endpoint of choice for assessing the efficacy of new therapies in advanced breast cancer, and provides a clear and unbiased measure of clinical benefit as well as ease and reliability of measurement [ 8, 9].

A team of scientists representing endocrinology, toxicology, chemistry, pathology, and statistics was involved in the creation of the study design, selection of endpoints, and choice of data analysis tools.

The results indicate that there is some degree of similarity regarding basic methodological elements such as selection of information sources, quality assessment of available evidence, choice of clinical endpoints, and choice of comparator(s).

The content of each SA question was scored according to predefined domains (quality, nonclinical, clinical, regulatory, and product information), their subdomains (e.g., efficacy), and a selection of additional content variables (e.g., endpoints, choice of active comparator).

In a clinical research context, the versatility of MMR makes it a method of choice for hypothesis generation on PRO endpoints, especially in phase II trials.

The mean is often the statistic of choice to define treatment effect sizes for HRQoL endpoints in most of these measures.

Additionally, at the third and most detailed level, each question was scored by a selection of content variables, e.g., primary endpoint, choice of active comparator, trial duration, and overall efficacy program.