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The study had 2 primary endpoints: measurement of periprosthetic BMD and implant subsidence measured as translation along the y-axis.
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Furthermore, all the investigators involved received a special training for endpoints measurements.
Protein concentration in undiluted BALF was measured by a standard endpoint measurement at 495 nm using Bradford reagent with a bovine serum albumin standard curve (Thermo Scientific, Rockford, IL).
Moreover, as an endpoint measurement, the signal in ddPCR is measured only after finishing the PCR amplification.
Absorbance was measured at 405 nm using a microtiter plate spectrophotometer followed by an endpoint measurement within one hour.
Achieving reliable endpoint measurement in trials of outpatient oral therapy may be difficult in ED setting, with higher loss to follow-up rate.
Efficacy analyses were performed on a modified intent-to-treat population, which included all randomized subjects who received at least 1 dose of study drug and obtained at least 1 endpoint measurement (mean change from baseline in the number of hours with headaches) after treatment.
Granulation scale up using the impeller power as the endpoint measurement, combined with a proper impeller blade design can significantly reduce expenditure and time and accelerate the progression of drug product to market, by eliminating stepwise series scale up, and minimizing drug substance requirements.
As operated here, LAMP is an exponential rate assay being assessed with an endpoint measurement.
In this model, mice are immunocompetent and the endpoint measurement is not mice survival but rather tissue colonization by the infection agent.
For endpoint measurement of cell death caused by drug toxicity, we used a widely accepted ATP assay that measures changes in ATP level as an indicator of cellular response to cell death.
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