Sentence examples for endpoints in the model from inspiring English sources
The establishment of anhedonia (lack of pleasure) is one of the major validated endpoints in the model of depression using rodents [2].
We suggest that the robust efficacy of anti-IL-13 mAb on disease-relevant endpoints in this model indicates where the benefit of anti-IL-13 therapeutics may be seen in clinical practice.
Thus we sought to discover whether 2B3-201 would be more effective than free steroid at improving the MRI, behavioural and histological endpoints in the SOD1 G93A model of ALS.
Since 36 linked transmission events had plasma HIV-1 measured at a visit prior to documented seroconversion, we used a sensitivity analysis to evaluate the use of the first positive HIV-1 test by either serology or RT-PCR as the endpoint in the Cox model.
The sequence allocation and study periods had no effect on the primary endpoint in the ANOVA model (p = 0.129 and p = 0.9503, respectively).
Although we also report findings in terms of quality-adjusted life years (QALYs) gained as a measure of benefit to patients and society of reducing disparities, the primary endpoints in modeling the employer perspective were direct medical care expenses and cost of days missed from work.
The main challenge in analyzing the relationship between the fingolimod exposure and the clinical endpoint was that the hill coefficient in the model could not be estimated successfully due to the lack of data at lower exposure levels (declining part of the relationship in Figure 2 ).
The ToxPredict application queries the Ontology service for all available models, along with the associated information about algorithms used in the model, descriptors, and endpoints.
All patients whose endpoint was not liver disease diagnosis were censored in the model.
For both endpoints, the combined classifier was the most significant variable in the model (see Additional data file 1).
