Sentence examples for endpoints for the development from inspiring English sources

Body weight, plasma glucose and HbA1c was collected and used as endpoints for the development of diabetes (Table  1).

It is exciting to observe that, with an increasing number of clinical therapeutic trials being designed; MRI may not only function as a diagnostic tool but may also have prognostic strength and thus serve as a surrogate endpoint for the development of new therapies.

This validated scale can then be used as a PD endpoint for the development of PD models for pain and/or sedation in children of different ages [ 32– 32].

Although these results are promising, until a blood-stage malaria vaccine demonstrates clinical efficacy, immune correlates of vaccine-induced protection and the choice of immunogenicity endpoints for clinical development decisions will remain a matter of reasoned conjecture.

However, until an AMA1 malaria vaccine demonstrates clinical efficacy against genetically diverse natural parasites, the relevance of growth inhibition assays and other humoral and cellular immunogenicity endpoints for clinical development decisions will remain a matter of reasoned conjecture.

Similarly, Broom and Johnson [ 138] listed measures indicating good and poor welfare that were used by Scharmann [ 139] for the development of humane endpoints in animal models.

Plasma oestradiol analysis has also provided a key pharmacodynamic endpoint in the development of inhibitors of aromatase, the enzyme responsible for oestrogen synthesis [ 1].

Statistical analyses included Cox regression for calculating risk ratios of survival endpoints and logistic regression for determining odds ratios for the development of loco-regional recurrences.

The principal endpoint for the study is the development of pneumonia.

The principal endpoint for the study was the development of pneumonia among acute stroke patients.

These observations establish a basis for the development of short term amphibian-based methods to evaluate thyroid axis effects using a suite of diagnostic endpoints.