Sentence examples for endpoint to determine from inspiring English sources

A modified 3 + 3 study design was used with the primary endpoint to determine the maximum tolerated dose of BV in this population.

In conclusion, consideration should be given to the use of CR rate as a phase II endpoint to determine if a particular regimen should be compared to the standard in a phase III setting for extensive-stage SCLC.

Synchrotron radiation micro-CT scans of the proximal tibia and fourth lumbar vertebrae were conducted ex vivo at the study endpoint to determine the degree and spatial distribution of the bone mineralization.

Therefore, the conventional metric and endpoint to determine the optimal phase 2 recommended dose is the experienced toxicity [3].

Data from smaller pilot investigations, using biomarkers as endpoint to determine whether a certain drug is reaching and acting on its biological target in patients with AD, would be very valuable when making a go/no-go decision for an expensive clinical trial with clinical improvement as the endpoint[2].

As a result, we used an average tumor size of 2000 mm as an endpoint to determine survival.

The need for defibrillation and institution of emergency cardiopulmonary bypass were major endpoints to determine the inability of the patient to tolerate displacement of the heart.

The CHC Trials with PRO Endpoints Search was designed to identify CHC clinical trials with PRO endpoints to determine whether PRO results show differentiation between treatments over time.

Examining multiple endpoints to determine whether a chemical leads to multiple metabolic disorders or only one or a subset of metabolic diseases.

However, exploratory analyses were performed on efficacy endpoints to determine if the observed differences in the two study groups were statistically significant.

Considering that these patients were treated with GnRHa for six months after surgery, we focused on two endpoints to determine short- and long-term surgical treatment efficacies.