Sentence examples for endpoint to detect from inspiring English sources

Lemons and coworkers [65] concluded therefore, that 'hyperecdysonism' might be a promising endpoint to detect and assess EDCs in arthropods inhabiting the terrestrial environment.

Opitz et al. [29] had evaluated the utility of mRNA expression of TSHα and TSHβ as a molecular endpoint to detect alteration in thyroid system function, which made up the methodological limitations in characterizing the thyroidal status of the differential treated tadpoles by means of analysis of serum T4, T3 and TSH concentrations.

The MN and BN assay with exfoliated buccal cells is a cost-effective, noninvasive method, in which the formation of anomalous cells is used as an endpoint to detect cytogenetic damage in exposed individuals.

Chi-square test or Fisher's Exact test was used for categorical variables and paired Student's t-test for continuous variables to compare socio-economic characteristics of respondents and outcome indicators at midterm and endpoint to detect changes throughout the SAHACOM lifespan.

In the present study, we investigated various morphological and molecular endpoints to detect thyroid system disruption in X. laevis tadpoles by the compounds DBP and MBP.

Because our primary endpoint was to detect a difference in number of analgesics consumed per month by patients between the two groups (see introduction), we divided G/G from non-G/G subjects and calculated the monthly mean of drug consumption: 21 non-G/G subjects consumed meanly 45.57 doses versus 32.93 doses of 15 G/G subjects (t = 1.887, P = 0.07, Cohen's d = 0.65).

Our primary endpoint was to detect tobacco insults to the respiratory epithelium and study the signs of possible repair after smoking cessation.

This endpoint was chosen to detect any potential underlying effect of active treatment on PD progression, with the assumption that a two-week washout period would remove all symptomatic LD effects, and any remaining differences in UPDRS scores between groups by this time would reflect treatment effects on disease progression.

As such, vtg is a common measurement endpoint in tests designed to detect certain classes of endocrine-disrupting chemicals (EDCs).

The primary endpoint was the proportion of patients without disease progression; secondary endpoints were time to disease progression (TTP), TTP in bone, best overall response rate, 1-year overall survival (OS) time, and safety; study not powered to detect endpoint differences.

This may mean the study was underpowered to detect endpoint changes in secondary outcomes, such as the severity of depression.