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The solution strategy focuses on 'learning by doing' using a value function that accounts for endpoint performance and feasibility.
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With DMFS as the endpoint, the performance measure reached a maximal value at approximately 5 years.
The primary endpoint was performance of the nurse using the guideline as the first part of a two-step screening process.
Secondary endpoints included performance for each item.
However, in a male rat fertility study with JNJ-26489112, a CNS-active agent, while there were no effects on histological endpoints, mating performance or pregnancy outcomes, sperm assessment was included.
To create a set V we start from the array T (see Figure 3) that contains a structural representation of the chemical compound, its measured activity (for a given endpoint) and predictive performance of each model from ℳ.
The secondary 6-months performance endpoint of effective biventricular pacing was achieved in 11 of the 12 evaluable patients (92%).
The primary 1-month performance endpoint of effective biventricular pacing was documented in 10 of the 12 evaluable patients (83%).
Signal detection analysis using 17 variables was applied to identify factors associated with OHCA outcomes; the primary endpoint was cerebral performance category (CPC) 1 or 2. A validation study was conducted to verify the model.
We applied different endpoints reflecting plant performance such as growth, pigment content, content in phenolic compounds, and plant stoichiometry.
The spectrum of endpoints displaying hormetic dose responses is also broad being inclusive of growth, longevity, numerous metabolic parameters, disease incidences (including cancer), various performance endpoints such as cognitive functions, immune responses among others.
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