Sentence examples for endpoint in the evaluation of from inspiring English sources
Stable disease is recognised as a significant endpoint in the evaluation of clinical benefit associated with many targeted agents, and a focus on only conventional complete or partial responses assessed in the conventional manner using RECIST[ 41 ] may underestimate efficacy and risk discontinuation of the development of active new agents[ 42 ].
Treatment-induced changes in proliferation are a useful intermediate endpoint for the evaluation of molecular relationships in breast carcinomas in vivo and for the assessment of drugs effecting these relationships.
A secondary endpoint is the evaluation of the immune response produced by the vaccine.
An exploratory endpoint also included the evaluation of changes in bone turnover marker levels and the rate of progressive disease in bone, defined as unequivocal progression of a pre-existing bone lesion or the appearance of a new bone lesion [10].
Third, the fact that EGFR-TKI therapy subsequently administered for relapse or progressive disease might obscure improved survival should be considered and accounted for in the evaluation of OS endpoints in current clinical practice.
In the evaluation of histological endpoints associated with HPV-16/18 HPV-16/18ved very high VE estimates in preventing CIN1+ and CIN2+ lesions, in line weth the high efficacy observedPvery/18 AS04-adjuvanted vaccine against CIN1+, CIN2+, and CIN3+ lesions thighwas obserVEd in a restimateseported large effinacy study (preventingCIN1+cted in 14 different countries during andollow-up period of 4 y.
He was categorized as a positive responder in the evaluation of the primary endpoint.
Secondary endpoints are the evaluation of treatment activity and exploratory evaluation of treatment efficacy.
Secondary endpoints were the evaluation of T-cell immune responses.
Secondary endpoints were the evaluation of TTP, overall survival (OS), and median time to response.
