Sentence examples for endpoint in the development of from inspiring English sources

The most sensitive toxicological endpoint in the development of the embryos was failure to hatch, which had an EC50 of 0.19 mg HCO1 l−1.

Plasma oestradiol analysis has also provided a key pharmacodynamic endpoint in the development of inhibitors of aromatase, the enzyme responsible for oestrogen synthesis [ 1].

The use of patient-reported outcomes as a secondary endpoint in the development of new antidepressants has been of growing interest in recent years.

The use of Patient-reported Outcomes (PROs) as secondary endpoints in the development of new antidepressants has grown in recent years.

Therefore, it seems logical to deprioritise the development of new in vitro methods to predict iritis as well as the use of this endpoint as reference in the development of in vitro testing strategies.

The primary endpoint was the development of lung injury in each study group.

This validated scale can then be used as a PD endpoint for the development of PD models for pain and/or sedation in children of different ages [ 32– 32].

The primary endpoint was the development of new AKI stages 2 3 from 12 h after admission up to 5 days.

The primary endpoint is the development of diabetes mellitus according to ADA criteria [ 29].

The primary endpoint was the development of PE or DVT during ICU stay.

Due to the long natural history of the disease, the improvement in hard endpoints [e.g., reduction in the development of liver-related outcomes (cirrhosis, variceal bleeds, ascites, hepatocellular carcinoma) and mortality] may not be feasible in a 2-year pivotal trial.