Your English writing platform
Free sign upSuggestions(1)
Exact(5)
Measurement of hyaline cartilage damage is viewed as a primary endpoint in the assessment of structural progression of knee osteoarthritis (OA).
In the last few decades, patient satisfaction has become an important endpoint in the assessment of the quality of care, which is increasingly required by accreditation agencies in monitoring of quality of hospital care.
While determination of phenotypic sex was a core endpoint in the assessment of the effects of E2 on sexual differentiation, a number of other gross abnormalities were also evaluated.
The implications of sexual dysfunction for treatment compliance and the prevention of relapse, together with the potential link between primary and secondary prolactinaemia and breast cancer and/or decreased bone mineral density [ 29] makes serum prolactin an important endpoint in the assessment of antipsychotic therapy.
For example, PFS was not considered a relevant endpoint in the assessment of various oncology drugs (e.g. abiraterone acetate, cabazitaxel and vemurafenib) and SVR was not considered relevant by IQWiG in the assessment of boceprevir and telaprevir for the treatment of hepatitis C.
Similar(55)
However, one should note that key validation criteria still need to be assessed before considering its use as a primary endpoint; in particular, the assessment of the responsiveness and test-retest reliability properties of the questionnaire and the estimation of the value for the minimal important difference.
A predefined secondary endpoint was the assessment of prognostic factors and biomarkers in CAP.
The primary endpoint was the assessment of the new neoadjuvant treatment.
Surrogate endpoints can be applied in the assessment of biological activity or clinical responses and perhaps in selection of patients most likely to respond to therapy.
In recent years, IVUS is also being performed as an endpoint for drug treatment trials in the assessment of atherosclerosis progression and/or regression.
The primary endpoint in this study was a reduction in Disease Activity Score (DAS), and secondary endpoints involved the assessment of American College of Rheumatology (ACR) criteria for reductions in tenderness and joint swelling scores.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.
Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com