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The ReCiPe endpoint assessment method is used in order to compare the scenarios.
Teferedegne, B., Lewis, J., Andrew, M., Peden, K. & Murata, H. Development of a neutralization assay for influenza virus using an endpoint assessment based on quantitative reverse-transcription PCR.
In addition to prototypical experimental design, methods for exposure route, sample collection, and endpoint assessment are described.
Twenty-two trainers, who received comprehensive training about POMA study design, pathobiology of OM, and endpoint assessment, educated staff at the 25 transplantation centres about OM assessment.
Therefore, it is recommended to identify the critical aspects for endpoint assessment, to optimize bioassays accordingly and to demonstrate the validity of the bioassay by testing known bioactive compounds [61].
This study required the development of experimental setup and endpoint assessment that were specific to the evaluated behavioural alteration, confirming the importance of this step also for behavioural assessment.
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The pharmacodynamic activity of individualised mutanome vaccines will need to be assessed by clinical, molecular and immunological endpoint assessments throughout the clinical development.
Blood was sampled for plasma concentration determination, and pharmacodynamic endpoint assessments were made during the study.
fParticipants who attended the baseline and endpoint assessments for both treatments included here.
For the completers analysis, only participants who attended the baseline and endpoint assessments for both treatments were included.
However, such endpoint assessments do not provide a comprehensive description of the dynamic changes in tumor hypoxia characteristics during exposure to a course of irinotecan-based chemotherapy, and no investigation to date has explored the feasibility and performance of hypoxia imaging for quantification of acute (i.e., hours) and chronic (i.e., days) hypoxia changes in such a setting.
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