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Fluorescent readings are acquired using endpoint analysis after PCR amplification.
Treated assay plates were incubated with compounds for 72 h and subsequently were developed for endpoint analysis using ATPLite.
A medical-device manufacturer used an inaccurate, but favorable, approximation in the primary endpoint analysis of a pivotal medical trial for a billion-dollar coronary stent.
Data from the letrozole 024 (LET 024) trial that compared letrozole and tamoxifen is used to illustrate a combined endpoint analysis that integrates both clinical and biomarker information.
Amplified genomic DNA was subjected to allele specific, single base extension endpoint analysis by mass spectrometry for inspection of the cystic fibrosis transmembrane regulator gene (NM_000492.3).
Three aspects of neoadjuvant endocrine therapy designs are considered: the determination of response; the assessment of surgical outcomes; and biomarker endpoint analysis.
While investigators designing clinical trials face the important issue of endpoint selection, an equally troublesome concern can be the a priori selection of the endpoint analysis.
Methods that study NK cell migration and cytotoxicity through endpoint analysis or live single cell imaging are also discussed.
The Per-Protocol dataset was used as the primary analysis set for the primary endpoint analysis.
Fig. 1 Flow diagram of patient enrolment and primary endpoint analysis.
The protocol required a baseline and 3-month MR study for the primary endpoint analysis (reduction in perfused fibroid volume).
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