Endorsing this hypothesis, using immunohistochemistry, we have demonstrated increasing 5αR1 protein levels in human liver with histological progression of NASH, which correlated with the presence of lobular inflammation; 5αR2 protein levels were unchanged across the NAFLD spectrum.
The increase of Blimp-1+ cells in the absence of galectin-3 endorses the hypothesis that galectin-3 is a potential regulator of Blimp-1 expression.
In conclusion, the differential expression of these enzymes belonging to the inositol phosphate pathway endorses the hypothesis that T. urticae synthesizes inositol which is involved in cryoprotection.
When it is endorsed, the hypothesis is regarded as more plausible, more probable, and more explanatory than relevant alternatives.
Our results endorse the hypothesis that under ventilation with a fixed frequency, the interactions between cardiac and respiratory fluctuations were stronger than in the case of patient driven modes of mechanical ventilation, as PSV and NAVA (2).
These results endorse the hypothesis that tumor regression was obtained by action of the endostatin released by the immunoisolated cells expressing this protein.
Our results endorse the hypothesis of an association between type 2 diabetes, mitochondrial dysfunction, and leukocyte-endothelium interaction.
Additionally, accumulation of hyperacetylated histones per se is not sufficient to cause growth inhibition (Brinkmann et al. 2001), endorsing the hypothesis that growth inhibition due to HDAC inhibitors is a complex process based upon direct modified gene expression and contributing effects of chromosomal or genomic instability.
This hypothesis is endorsed by a recent study which showed more appropriate use of injectables in China versus oral tablets, in line with WHO recommendations, once the procurement incentives had been removed coupled with programmes to enhance the rational use of medicines [ 36].
Whilst a body of evidence supports this hypothesis, other data endorse the view that atrophy of RGC perikarya occurs first [ 45].
