Sentence examples for endogenous toxicity from inspiring English sources

The superfamily of these metabolic enzymes functions as important players in protecting the cells from oxidative damage and endogenous toxicity [ 67].

The additive effect of wtSOD1 aggregates on the mouse phenotype supports a hypothesis that wtSOD1 per se also has an endogenous ALS-associated toxicity; this endogenous toxicity is enhanced by mutations; this endogenous toxicity is likely derived from the propensity to SOD1 aggregation.

Our findings indicate that apoptosis due to PPARγ inhibition is consistent with endogenous palmitate toxicity.

Endogenous palmitate toxicity represents a genetically based property of ERBB2-positive breast cancer that can be exploited for therapeutic intervention.

Failing metal homeostasis in DRG neurons may contribute to endogenous Zn toxicity whereas Fe sequestration in holoferritin of hyperplastic satellite cells may be neuroprotective.

Dineley et al. [ 19, 20] summarized the evidence of endogenous Zn toxicity in the CNS, in which mitochondria bear the brunt of the damage.

Many questions remain: Does frataxin deficiency trigger endogenous metal toxicity; and why do DRG in FA retain Zn and Fe rather than shedding the metals into the blood stream?

It can be used as an endogenous A β toxicity cell model instead of incubating cells with exogenous A β.

The adjacent gene SAT5 encodes a putative acetyltransferase, and so the two together may effect endogenous protection from toxicity in the same manner as Tri8 and Tri101 of Fusarium [ 36].

The inhibitory effects are supposed to be owing to limited activities of soil endogenous microorganisms, potential toxicities of CNTs to the microorganisms, and reduced bioavailability of 2,4-DCP in the presence of CNTs, even though a desorption hysteresis of 2,4-DCP on CNTs was not observed.

Toxicity of endogenous P5C accumulation was postulated on the basis of proline-induced toxicity of P5C-dehydrogenase deficient mutants, although a more recent study did not observe toxic effects of externally applied P5C [ 23- 25].