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Four endogenous specific inhibitors of MMPs have been described: TIMP-1, -2, -3 and -4 [ 2**, 12**].
The peptide sequence of the endogenous, specific inhibitor, calpastatin, is known and the inhibition mechanism has been elucidated 33, 34.
Another target of special interest concerns bacterial protein phosphorylation by endogenous specific enzymes, which represents a promising way toward the discovery of non-conventional antibacterial drugs.
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Plasmid endogenous-specific biotinylated primers were used for PCR amplification.
Calpastatin is the only known endogenous-specific inhibitor of the conventional calpains.
Detection of exogenously spliced MADD or RON was detected with an endogenous-specific forward primers and a plasmid-specific reverse primer (pINDr).
Loss of function or deletion of p16ink4a (endogenous Cdk4/6 specific inhibitor protein) frequently occurs in clinical cancer cells.
In order to design endogenous TdPDS specific primers, we cloned a longer fragment of TdPDS.
We suspect that endogenous mediators, specific to ongoing inflammation, prevail over proresolution signals in terms of regulating cell clearance.
They were used to evaluate the endogenous controls specific for peripheral blood that exhibit minimal differential expression.
firstly endodormancy: the deepest state of dormancy, in which bud burst is prevented by endogenous factors specific to the meristem.
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