Sentence examples for endogenous modifications from inspiring English sources

Additionally, endogenous modifications were also performed, including the overproduction of the xylulokinase Xks1p and the non-oxidative PPP (pentose phosphate pathway), and the inactivation of the aldose reductase Gre3p and the alkaline phosphatase Pho13p.

It is thus concluded that the endogenous modifications can be visualized by using fluorescently labeled Fab without affecting cell function.

While other techniques such as FRET-based sensors can also monitor epigenetic regulation in living cells, in particular the balance between the modifying and demodifying enzymes, they cannot quantify the endogenous modifications themselves even though they seem to be suitable for assaying the effects of inhibitors (Sasaki et al. 2012).

We named this technique Fab-based live endogenous modification labeling, or FabLEM (Hayashi-Takanaka et al. 2011).

Cytosine methylation is the most frequent endogenous modification of DNA in eukaryotes and is involved in regulating gene expression [ 1].

In Fab-based live endogenous modification labeling (FabLEM), fluorescently labeled antigen-binding fragments (Fabs) are loaded into cells.

Cytosine methylation is the only known endogenous modification of DNA in mammals and it occurs through DNA methyltransferase-mediated methylation [ 137].

Here again we could validate the endogenous modification of RTN4 by ISG15 following Listeria infection by detecting multiple distinct slower migrating bands of RTN4 and ISG15.

mA is the most abundant endogenous modification for mRNA in eukaryotes [49]; and the recent discoveries of two novel mA demethylases have gained renewed interest for this long-known modification [50,51].

Even though electrospray ionization can produce oxidation, given that a similar analysis of the Dam1 complex did not show any obvious oxidation, the oxidized Pyrococcus furiosus proteoforms may represent an endogenous modification.

However, toxicity could be triggered, related to endogenous proteins modifications at the NP surface.