Sentence examples for endogenous island from inspiring English sources
It is unknown what DNA sequences in these elements generate exceptions to the DNA methylation patterns observed for the majority of the MiniPs, but interestingly for one of these (CARTPT) the endogenous island shows DNA hypermethylation at the endogenous promoter.
Thirty-seven of 57 target genes contained a promoter CpG island, which was generally truncated in MiniPs compared to the endogenous islands (Supporting Information, Table S1).
A detection system for demethylating agents using an endogenous promoter CpG island was reported [ 10], but fluorescence cannot be quantified so precisely using only imaging and the results may overlook the confounding cytochromes P450 activation effect of environmental pollutants in hepatic cells.
One study reports on the establishment of a detection system for demethylating agents using an endogenous promoter CpG island [ 10], but the HCT 116 cell line is a poor candidate tool due to its relative absence of the cytochromes P450 enzymes and corresponding activation of pollutants.
Comparisons were made between mainland settlers and people endogenous to the islands, where both categories of people had received yoga.
To further verify the effect of endogenous PTEN on blood islands formation, we employed VE-Cadherin in situ hybridization as blood islands marker following downregulating PTEN with PTEN siRNA and GFP co-transfection (Fig. 4F,G).
Only Brava and Fogo islands showed an endogenous CO2 contribution with δ13C (CO2) values higher than those representative of a volcanic-hydrothermal source (Camarda et al. 2007).
These constructs, however, gave much greater variability in levels of expression than those observed in our previous work with a larger CpG island fragment and the endogenous RNP promoter.
Importantly however, at CG densities that are more representative for islands, the methylation of endogenous and inserted fragments starts to significantly deviate.
The "endogenous hazards" and "intrinsic vulnerability" that exist on the island (Pelling and Uitto 2001; Lewis 2009) can be understood as a complex reality.
