Sentence examples for endogenous functions from inspiring English sources
As with the human CYP genes, the CYP genes in zebrafish occur in two major functional groups: those families that include enzymes involved primarily in endogenous functions (CYP families 5-51; Table 1); and those that include enzymes involved heavily in oxidation of xenobiotics (CYP families 1-3, and to a lesser degree family 4; Table 2).
The endogenous functions of methylated/demethylated forms of PP2A in mammalian systems have not yet been explicitly tested.
In this report, we focused towards the identification of novel CypB-binding proteins in kidney, in order to: i) learn more about the endogenous functions of CypB and ii) unravel, in part, the molecular mechanisms of CsA-induced kidney toxicity.
Thus, identifying this novel negative regulatory feedback loop involving RelB could be particularly useful as an adjunctive therapeutic approach for HAND, peripheral HIV infection, or even other neurologic or immune diseases, since overexpression of RelB in microglial cells does not completely block Tat-induced release of TNFα, which would negatively impact TNFα's other endogenous functions.
It is not clear which, if any, endogenous functions of FUS are involved in disease pathogenesis.
Using miR-21 Sponge in renal cancer cells to block endogenous function of miR-21, we show inhibition of phosphorylation of p65 subunit of NFκB, IKKβ and IκB, which results in attenuation of NFκB transcriptional activity.
Their endogenous function within an animal is unknown, but may involve regulating energy expenditure.
To investigate the endogenous function, we knocked down MBP-1 expression in HFF by RNA interference.
Importantly, the endogenous function and substrate(s) of PfCRT remain unknown.
The endogenous function of the family of HKT transporters and their role in Na+ transport and provision of salinity tolerance to plants has been reviewed recently [8].
